Strobel C T, Byrne W J, Fonkalsrud E W, Ament M E
Ann Surg. 1978 Sep;188(3):394-403. doi: 10.1097/00000658-197809000-00015.
Although home parenteral nutrition (HPN) has been used successfully for adult patients, no extensive experience with children has been reported. During the past three years, we have managed 34 patients, ages 1 1/2 months to 20 1/2 years, on a HPN program for periods ranging from 23 to 786 days. Silastic Broviac catheters were inserted into the superior vena cava through the jugular or cephalic veins or into the inferior vena cava through the saphenous vein. The catheters were brought out onto the chest or lower abdominal wall through a subcutaneous tunnel. Solutions were infused over a 10--14-hour period each day, using a volumetric pump system. All patients improved their nutritional status. Twenty-three of 29 on the program for more than two months showed an increase in height. All patients evidenced a significant decrease in symptomatology. All resumed per group activities while on HPN and were able to continue their education or work. At present 24 patients including 15 with Crohn's disease no longer receive HPN. Administration of HPN through a Broviac catheter is a safe, successful technique for maintaining an optimal nutritional status in children with severe digestive disorders, and permits resumption of a more normal daily lifestyle. Following HPN, bowel adaptation and initiation of full oral alimentation become possible in many patients.
尽管家庭肠外营养(HPN)已成功应用于成年患者,但尚未有关于儿童的广泛经验报道。在过去三年中,我们对34例年龄从1个半月至20岁半的患者实施了HPN计划,时间从23天至786天不等。硅橡胶Broviac导管通过颈静脉或头静脉插入上腔静脉,或通过大隐静脉插入下腔静脉。导管通过皮下隧道引出至胸壁或下腹部壁。使用容量泵系统,每天在10 - 14小时内输注营养液。所有患者的营养状况均得到改善。在该计划中接受治疗超过两个月的29例患者中有23例身高增加。所有患者的症状均明显减轻。所有患者在接受HPN期间都恢复了日常活动,并能够继续接受教育或工作。目前,包括15例克罗恩病患者在内的24例患者不再接受HPN。通过Broviac导管进行HPN是一种安全、成功的技术,可维持患有严重消化系统疾病儿童的最佳营养状况,并使他们能够恢复更正常的日常生活方式。在接受HPN后,许多患者的肠道得以适应,并能够开始完全经口进食。