Sato E I, Hatta F S, Levy-Neto M, Fernandes S
Universidade Federal de São Paulo, Brazil.
Int J Cardiol. 1998 Oct 1;66 Suppl 1:S67-70; discussion S71. doi: 10.1016/s0167-5273(98)00152-1.
We collected clinical, demographic, and angiographic data of Takayasu arteritis (TA) patients followed at Rheumatology Division of three Public University Centers (UNIFESP, USP, and UNICAMP) located in São Paulo State, Brazil. Clinical and demographic data were obtained from 73 patients (61 female; 50 white) The mean age at time of diagnosis was 27 y.o. and the mean follow-up time was 5 years. The following clinical features were observed along the evolution of these patients: absent or reduced pulses in upper limbs (85%), arterial bruit (64.5%), claudication of upper members (57%), headache (45%), hypertension (35.5%), dizziness (29%), cardiac bruit (29%), weight loss (27.5%), arthralgia or arthritis (26%), fever (24.5%) and claudication of lower limbs (20.5%). According to new angiographic classification of Takayasu arteritis performed in 28 patients followed at UNTFESP, with routine full aortography, 21% were classified as type I, 4% as type IIa, 4% as type III, 14% as type IV and 57% as type V. No patients had type IIb. Patients with Takayasu arteritis in São Paulo State Brazil showed female predominance and arterial involvement pattern similar to the one observed in Japan, with more than 20% classified as type I with exclusive involvement of the branches from the aortic arch.
我们收集了位于巴西圣保罗州的三所公立大学中心（圣若泽杜斯坎普斯联邦大学、圣保罗大学和坎皮纳斯州立大学）风湿病科随访的大动脉炎（TA）患者的临床、人口统计学和血管造影数据。临床和人口统计学数据来自73例患者（61例女性；50例白人）。诊断时的平均年龄为27岁，平均随访时间为5年。在这些患者的病程中观察到以下临床特征：上肢脉搏消失或减弱（85%）、动脉杂音（64.5%）、上肢间歇性跛行（57%）、头痛（45%）、高血压（35.5%）、头晕（29%）、心脏杂音（29%）、体重减轻（27.5%）、关节痛或关节炎（26%）、发热（24.5%）和下肢间歇性跛行（20.5%）。根据在圣若泽杜斯坎普斯联邦大学随访的28例患者中进行的大动脉炎新血管造影分类，采用常规全主动脉造影，21%被分类为I型，4%为IIa型，4%为III型，14%为IV型，57%为V型。没有患者为IIb型。巴西圣保罗州的大动脉炎患者以女性为主，动脉受累模式与在日本观察到的相似，超过20%被分类为I型，仅主动脉弓分支受累。
