Läuffer J M, Baer H U, Schajor M, Halter F, Büchler M W
Department for Visceral and Transplantation Surgery, University Hospital, Inselspital, Bern, Switzerland.
Hepatogastroenterology. 1998 Nov-Dec;45(24):2339-43.
Adenocarcinomas of the bifurcation of the hepatic ducts (Klatskin tumors) are a relatively rare cause of obstructive jaundice. Differential diagnosis includes other neoplastic lesions, sclerosing cholangitis, Mirizzi's syndrome and benign strictures. We present a 46 year-old white female with a 2 month history of epigastric pain and progressive jaundice. Endoscopic retrograde cholangiopancreaticography (ERCP) revealed a filiform stenosis of the right hepatic duct and an obstructed left hepatic duct, an image strongly suggestive of a Klatskin tumor. The correct diagnosis was achieved, however, by percutaneous transhepatic cholangiography (PTC), which disclosed a gallstone at the common hepatic duct bifurcation and multiple small concrements in the left hepatic duct. After endoscopic removal of the gallstones in the biliary tree and laparoscopic cholecystectomy, the patient was discharged on the third post-operative day. Protuberant tumors and round biliary stones may be confused at ERCP.
肝门部胆管癌(Klatskin瘤)是梗阻性黄疸相对少见的病因。鉴别诊断包括其他肿瘤性病变、硬化性胆管炎、Mirizzi综合征和良性狭窄。我们报告一名46岁白人女性,有2个月的上腹部疼痛和进行性黄疸病史。内镜逆行胰胆管造影(ERCP)显示右肝管丝状狭窄和左肝管梗阻,此影像强烈提示为Klatskin瘤。然而,经皮经肝胆管造影(PTC)做出了正确诊断,发现肝总管分叉处有一枚胆结石,左肝管内有多个小结石。在内镜下取出胆道树中的胆结石并进行腹腔镜胆囊切除术后,患者术后第3天出院。在ERCP检查中,突出的肿瘤和圆形胆石可能会混淆。