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反映芬兰桑拿中交感神经活动的激素变化。

Change in hormones reflecting sympathetic activity in the Finnish sauna.

作者信息

Lammintausta R, Syvälahti E, Pekkarinen A

出版信息

Ann Clin Res. 1976 Aug;8(4):266-71.

PMID:999213
Abstract

The effects of the high temperature (80-120 degrees C) of the Finnish Sauna bath on the concentrations of growth hormone, immunoreactive insulin and renin activity in plasma, on blood glucose and on the urinary excretion of aldosterone, vanilmandelic acid and sodium of 55 healthy volunteers were studied. There was a significant increase in mean heart rate (62%), serum growth hormone (142%) and plasma renin activity (95%) in the Sauna. One hour after the Sauna bath the mean serum growth hormone had returned to the control level while plasma renin activity still remained higher (p less than 0.05) than before the Sauna bath. The serum insulin, blood sugar and urinary excretion of aldosterone and VMA did not change during or after Sauna bath. The urinary sodium excretion decreased significantly after the Sauna bath and the decrease was most striking (46%) during the first 6-hour period from the beginning of Sauna bath. Plasma renin activity values correlated positively with 12-hour urinary VMA excretion (p less than 0.01) and negatively with 6-hour urinary sodium excretion (p less than 0.05) before and after Sauna, suggesting the role of catecholamines and sodium depletion in renin response in Sauna.

摘要

研究了芬兰桑拿浴高温(80 - 120摄氏度)对55名健康志愿者血浆中生长激素、免疫反应性胰岛素和肾素活性浓度、血糖以及醛固酮、香草扁桃酸和钠的尿排泄量的影响。桑拿浴时平均心率显著增加(62%),血清生长激素增加(142%),血浆肾素活性增加(95%)。桑拿浴1小时后,血清生长激素平均水平恢复到对照水平,而血浆肾素活性仍高于桑拿浴前(p < 0.05)。桑拿浴期间及之后,血清胰岛素、血糖以及醛固酮和香草扁桃酸的尿排泄量均未改变。桑拿浴后尿钠排泄显著减少,且从桑拿浴开始的最初6小时内减少最为明显(46%)。桑拿浴前后,血浆肾素活性值与12小时尿香草扁桃酸排泄量呈正相关(p < 0.01),与6小时尿钠排泄量呈负相关(p < 0.05),提示儿茶酚胺和钠耗竭在桑拿浴肾素反应中的作用。

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