Kuo T, Uhlemann J, Reinhard E H
Arch Dermatol. 1976 Sep;112(9):1302-3.
An asymptomatic skin nodule in a patient with myelofibrosis was shown to consist of extramedullary hematopoiesis. It was a soft bluish nodule that resembled a hemangioma. Microscopically, both erythroid and myeloid cells, but not megakaryocytes, were found. This case demonstrates the ability of the skin to recapitulate dermal hematopoiesis seen in a stage of human fetal development.
一名骨髓纤维化患者的无症状皮肤结节经检查显示由髓外造血组成。它是一个柔软的蓝色结节,类似血管瘤。显微镜下发现了红系和髓系细胞,但未发现巨核细胞。该病例证明了皮肤再现人类胎儿发育阶段所见真皮造血的能力。