弗里德赖希共济失调：一些系谱研究的初步结果

Friedreich's ataxia: preliminary results of some genealogical research.

作者信息

Barbeau A, Le Siege M, Breton G, Coallier R, Bouchard J P

出版信息

Can J Neurol Sci. 1976 Nov;3(4):303-6. doi: 10.1017/s0317167100025488.

Abstract

A preliminary genealogical investigation of all the known ancestors from the year 1608 of 4 apparently unrelated French Canadian kindreds with Friedreich's ataxia reveals that the original ataxia gene in the province of Quebec was present within a core of no more than 10 families living in Quebec City in the mid-1600's.

摘要

对4个明显无亲缘关系的法裔加拿大弗里德赖希共济失调家族自1608年起的所有已知祖先进行的初步谱系调查显示，魁北克省最初的共济失调基因存在于17世纪中叶居住在魁北克市的不超过10个家族的核心群体中。