Meglio M, Ianelli A, Anile C, Rossi G F
Epilepsia. 1976 Dec;17(4):449-59. doi: 10.1111/j.1528-1157.1976.tb04457.x.
In acute experiments in the rabbit, the amygdaloid nuclear complexes of the two sides were made epileptogenic through electrical stimulation or local injection of penicillin in gel. The effects on the epileptic pattern produced by surgical removal of one of the two epileptogenic amygdalae and the effects of sterotactic lesioning of the region of anterior commissure, head of caudate nucleus, and occipital cortex were analyzed. The occurrence of phenomena of both inhibitory and facilitatory interaction between the two epileptogenic amydalae was confirmed. In some experimental conditions, the restraining influence of an amygdaloid penicillin focus on the contralateral one was quite relevant, and its effect could persist even after surgical removal of the focus from which it originated. The mediation of the interamygdadoid epileptic interaction could not be ascribed to a single cerebral structure or anatomofunctionally homogenous group of structures. The phenomenon appears to involve several structures at different encephalic levels.
在对家兔进行的急性实验中，通过电刺激或局部注射凝胶青霉素使双侧杏仁核复合体产生癫痫病灶。分析了手术切除两个致痫杏仁核之一对癫痫发作模式的影响，以及对前连合区域、尾状核头部和枕叶皮质进行立体定向损伤的影响。证实了两个致痫杏仁核之间存在抑制性和促进性相互作用的现象。在某些实验条件下，杏仁核青霉素病灶对侧病灶的抑制作用相当显著，甚至在手术切除其起源病灶后，这种作用仍可持续。杏仁核间癫痫相互作用的介导不能归因于单一的脑结构或解剖功能上同质的结构组。这种现象似乎涉及不同脑水平的多个结构。
