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性质不明的短暂性麻痹发作:非惊厥性癫痫发作性麻痹问题

Transient paralytic attacks of obscure nature: the question of non-convulsive seizure paralysis.

作者信息

Fisher C M

出版信息

Can J Neurol Sci. 1978 Aug;5(3):267-73. doi: 10.1017/s0317167100024331.

Abstract

Eleven patients with transient paralytic attacks of obscure nature are described. Paralysis could involve face or leg alone, face and hand, or face, arm and leg. The duration varied from two minutes to one day. Four patients had brain tumors, six probably had brain infarcts, and one a degenerative process. The differential diagnosis included TIAs, migraine accompaniments, and seizures. In the absence of good evidence for the first two, the cases are discussed from the standpoint of possibly representing nonconvulsive seizure paralysis (ictal paralysis, inhibitory seizure paralysis or somatic inhibitory seizure). Because of the difficulty in defining seizures as well as TIAs and migraine in their atypical variations, a firm conclusion concerning the mechanisms of the spells was not attained. Two cases of the hypertensive amaurosis-seizure syndrome have been added as further examples of ictal deficits.

摘要

本文描述了11例性质不明的短暂性麻痹发作患者。麻痹可仅累及面部或腿部、面部和手部,或面部、手臂和腿部。持续时间从两分钟到一天不等。4例患者患有脑肿瘤,6例可能发生了脑梗死,1例有退行性病变。鉴别诊断包括短暂性脑缺血发作(TIA)、偏头痛伴发症状和癫痫发作。由于缺乏前两者的有力证据,从可能代表非惊厥性癫痫发作性麻痹(发作性麻痹、抑制性癫痫发作性麻痹或躯体抑制性癫痫)的角度对这些病例进行了讨论。由于难以将癫痫发作以及非典型变异的TIA和偏头痛进行明确界定,因此未能就发作机制得出确切结论。另外增加了2例高血压性黑蒙-癫痫综合征病例作为发作性缺损的进一步实例。

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