Danoff B F, Pripstein S, Croce N, Kramer S, Lee K F
Cancer. 1978 Sep;42(3):1066-72. doi: 10.1002/1097-0142(197809)42:3<1066::aid-cncr2820420305>3.0.co;2-o.
Radiotherapy plays a major role in the management of pituitary adenomas, either as a surgical adjunct or as the primary form of treatment. Small field precision techniques are utilized. The ability to employ limited field therapy and produce local control rates of 80--90% demands precise tumor localization. The extrasellar extension of pituitary adenomas has classically been demonstrated on angiographic and pneumoencephalographic examinations. Direct superior extension is accurately delineated by these examinations; lateral extension, however, is not and the total anterior-posterior extent of the tumor may be underestimated. The addition of computerized tomography significantly increases the information available in the assessment of tumor extension and the subsequent accuracy of treatment planning for radiotherapeutic purposes.
放射治疗在垂体腺瘤的治疗中起着重要作用，可作为手术辅助手段或主要治疗方式。采用小视野精确技术。运用有限野治疗并实现80%至90%的局部控制率，这需要精确的肿瘤定位。垂体腺瘤的鞍外扩展传统上通过血管造影和气脑造影检查来显示。这些检查能准确描绘肿瘤直接向上的扩展；然而，对于侧向扩展却无法准确显示，肿瘤的前后总范围可能会被低估。计算机断层扫描的加入显著增加了评估肿瘤扩展时可获得的信息，以及后续放射治疗计划的准确性。
