Rennie J A, Ogston D
Haemostasis. 1976;5(4):258-64. doi: 10.1159/000214141.
The whole blood clotting time, plasma fibrinogen and individual coagulation factors II, V, VII, VIII, IX, X, XI, and XII were serially measured in 14 patients over a 10-day period following acute myocardial infarction. A further six patients with similar symptoms but without evidence of myocardial infarction were also studied. The whole blood clotting time was significantly shorter within the first 24 h after infarction than on subsequent days. There were significant increases in the levels of fibrinogen and of factors VIII, IX, and XI and a significant decrease in factor XII in the patients who had sustained a myocardial infarction. The patients without myocardial infarction had no significant change in any of the coagulation factors measured.
在14例急性心肌梗死患者发病后的10天内，连续测定其全血凝血时间、血浆纤维蛋白原以及凝血因子II、V、VII、VIII、IX、X、XI和XII。另外还研究了6例有类似症状但无心肌梗死证据的患者。梗死发生后的头24小时内全血凝血时间明显短于随后几天。发生心肌梗死的患者纤维蛋白原、因子VIII、IX和XI水平显著升高，因子XII水平显著降低。无心肌梗死的患者所测凝血因子均无显著变化。
