[I型和II型糖尿病患者的肾移植]

[Kidney transplantation in patients with type I and type II diabetes mellitus].

作者信息

Baptista C, Bastos M, Gomes L, Macário F, Ruas L, Rodrigues D, Alves R, Gomes H, Ferreira C, Roseiro A, Paiva S, Barros L, Carvalheiro M, Mota A, Furtado A L, Ruas M M

机构信息

Serviço de Endocrinologia, Diabetes e Metabolismo, Hospitais da Universidade de Coimbra.

出版信息

Acta Med Port. 1998 Nov;11(11):943-6.

PMID:10021792

Abstract

A total of 618 patients with end-stage renal disease received kidney transplants between 1980 and September 1996. Twenty eight of them were diabetics. Better results were achieved for type 1 diabetic patients than for type 2 (mortality: 5.9% vs 27.3%; functioning graft: 88.2% vs 72.7%). The morbility was also higher in those patients (infections: 81.8% vs 29.4%; vascular complications: 45.5% vs 17.6%). Actuarial patient and graft survival were lower for type 2 than for non diabetic patients. For type 1 diabetics the results are similar to those for non diabetics. Better results can probably be achieved by restricting the selection criteria. The decision to transplant or maintain on dialysis should be made on a case by case basis.

摘要

1980年至1996年9月期间，共有618例终末期肾病患者接受了肾移植手术。其中28例为糖尿病患者。1型糖尿病患者的治疗效果优于2型糖尿病患者（死亡率：5.9%对27.3%；移植肾存活：88.2%对72.7%）。这些患者的发病率也更高（感染：81.8%对29.4%；血管并发症：45.5%对17.6%）。2型糖尿病患者的患者和移植肾精算生存率低于非糖尿病患者。对于1型糖尿病患者，结果与非糖尿病患者相似。通过限制选择标准可能会取得更好的效果。是否进行移植或维持透析应根据具体情况决定。