Muckle D S
Injury. 1976 Nov;8(2):98-101. doi: 10.1016/0020-1383(76)90041-3.
A study of 200 femoral neck fractures in ambulant patients showed that 62 per cent of subcapital and 58 per cent of trochanteric fractures occurred without a significant history of injury. It was also observed that almost 70 per cent of patients in this group were on long-term medication which could affect bone density. In the remaining patients with a definite history of injury, only 20 per cent and 21 per cent respectively were on long-term therapy, figures which corresponded to the 18 per cent of patients on prolonged medication attending with minor injuries (age- and sex-matched). The action of corticosteroids, thyroxine, phenobarbitone, phenytoin, frusemide and bendrofluazide on bone density and their responsibility for femoral neck fractures are discussed.
一项针对200例能行走患者股骨颈骨折的研究表明，62%的头下型骨折和58%的转子间骨折发生时并无明显受伤史。还观察到，该组中近70%的患者正在接受可能影响骨密度的长期药物治疗。在其余有明确受伤史的患者中，分别只有20%和21%正在接受长期治疗，这一数字与因轻伤前来就诊（年龄和性别匹配）且正在接受长期药物治疗的患者比例18%相符。文中讨论了皮质类固醇、甲状腺素、苯巴比妥、苯妥英、速尿和苄氟噻嗪对骨密度的作用及其与股骨颈骨折的关系。
