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可卡因戒断症状学与治疗损耗

Cocaine abstinence symptomatology and treatment attrition.

作者信息

Mulvaney F D, Alterman A I, Boardman C R, Kampman K

机构信息

University of Pennsylvania School of Medicine, Department of Psychiatry, Veterans Affairs Medical Center, Philadelphia 19104, USA.

出版信息

J Subst Abuse Treat. 1999 Mar;16(2):129-35. doi: 10.1016/s0740-5472(98)00017-8.

Abstract

Premature termination from outpatient cocaine treatment predicts a number of poor outcomes, including higher rates of relapse and unemployment. This study attempted to predict dropouts from outpatient cocaine treatment, as well as those unable to achieve initial abstinence from cocaine, using two baseline variables that had previously been shown to predict treatment dropout: a measure of the severity of cocaine abstinence symptomatology using the Cocaine Selective Severity Assessment (CSSA) and the initial urine toxicology. Results of logistic regression analyses indicated that those with more intense abstinence symptoms, as measured by the CSSA, were five times more likely to terminate treatment prematurely. When combined with the CSSA, the initial urine did not significantly predict dropouts. The CSSA and the baseline urine were equal in their ability to predict those who would fail in their initial attempts to achieve abstinence. Implications for treatment are discussed.

摘要

门诊可卡因治疗的提前终止预示着一系列不良后果,包括更高的复发率和失业率。本研究试图利用两个先前已被证明可预测治疗中断的基线变量,来预测门诊可卡因治疗的退出者以及那些无法实现可卡因初始戒断的人:一个使用可卡因选择性严重程度评估(CSSA)来衡量可卡因戒断症状严重程度的指标,以及初始尿液毒理学检测。逻辑回归分析结果表明,以CSSA衡量,有更强烈戒断症状的人提前终止治疗的可能性高出五倍。当与CSSA结合时,初始尿液检测并不能显著预测退出者。CSSA和基线尿液在预测那些初始戒断尝试会失败的人方面能力相当。文中讨论了对治疗的启示。

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