Pomp D, Nielsen M K
Department of Animal Science, University of Nebraska, Lincoln 68585-0908, USA.
Obes Res. 1999 Jan;7(1):106-10. doi: 10.1002/j.1550-8528.1999.tb00397.x.
Evidence for quantitative genetic variation in components of energy balance in animals is overwhelming. Much of this evidence is drawn from livestock species and relevant rodent models, especially long-term selection lines. This mini-review summarizes findings from several animal studies that have characterized quantitative genetic variation in energy intake and energy expenditure. Applications of this information toward understanding and treatment of human obesity are explored.
动物能量平衡各组成部分存在数量遗传变异的证据极为充分。这些证据大多来自家畜物种和相关啮齿动物模型,尤其是长期选择品系。本综述总结了多项动物研究的结果,这些研究对能量摄入和能量消耗中的数量遗传变异进行了特征描述。并探讨了该信息在理解和治疗人类肥胖症方面的应用。