Gordon S B, Curran A D, Fishwick D, Morice A H, Howard P
Department of Medicine and Pharmacology, University of Sheffield, Royal Hallamshire Hospital, UK.
Occup Med (Lond). 1998 Oct;48(7):455-9. doi: 10.1093/occmed/48.7.455.
Glass bottle workers have been shown to experience an excess of respiratory symptoms. This work describes in detail the symptoms reported by a cohort of 69 symptomatic glass bottle workers. Symptoms, employment history and clinical investigations including radiology, spirometry and serial peak expiratory flow rate records were retrospectively analyzed from clinical records. The results showed a consistent syndrome of work-related eye, nose and throat irritation followed after a variable period by shortness of breath. The latent interval between starting work and first developing symptoms was typically 4 years (median = 4 yrs; range = 0-28). The interval preceding the development of dysponea was longer and much more variable (median = 16 yrs; range = 3-40). Spirometry was not markedly abnormal in the group but 57% of workers had abnormal serial peak expiratory flow rate charts. Workers in this industry experience upper and lower respiratory tract symptoms consistent with irritant exposure. The long-term functional significance of these symptoms should be formally investigated.
玻璃瓶工人已被证明会出现过多的呼吸道症状。这项研究详细描述了一组69名有症状的玻璃瓶工人所报告的症状。从临床记录中回顾性分析了症状、就业史以及包括放射学、肺活量测定和连续呼气峰值流速记录在内的临床检查结果。结果显示，出现了与工作相关的眼睛、鼻子和喉咙刺激的一致综合征，在一段可变的时间后出现呼吸急促。开始工作到首次出现症状的潜伏期通常为4年（中位数 = 4年；范围 = 0 - 28年）。呼吸困难出现前的间隔时间更长且变化更大（中位数 = 16年；范围 = 3 - 40年）。该组的肺活量测定没有明显异常，但57%的工人连续呼气峰值流速图表异常。该行业的工人经历了与刺激性暴露相符的上呼吸道和下呼吸道症状。这些症状的长期功能意义应进行正式调查。
