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[侵袭性肺及纵隔肿瘤需行上腔静脉重建的手术策略]

[Surgical strategy for invasive pulmonary and mediastinal tumors requiring superior vena cava reconstruction].

作者信息

Okada M, Sugimoto T, Yamamoto H

机构信息

Department of Surgery, Kobe University School of Medicine, Japan.

出版信息

Kyobu Geka. 1999 Jan;52(1):14-8.

Abstract

During the past 16 years, 22 patients were operated on concomitantly with superior vena cava (SVC) reconstruction in our university hospital. Among them, 19 patients had anterior mediastinal tumor and 3 advanced lung cancer. They were 13 males and 9 females, ranging in age from 16 to 70 (mean, 51.4) years. Severe SVC syndrome was found in 10 cases of them. The anterior mediastinal tumors consisted of invasive thymoma in 10 cases, thymic Hodgkin's disease in 2, seminoma in 2, and thymic cancer, thymic carcinoid, thyroid cancer, metastasis of chondrosarcoma and yolk sac tumor in each one. Regarding SVC reconstruction, anatomical bypass was performed in 18 cases, in addition to a radical resection of the tumor. The left innominate vein was reconstructed in 5, the right innominate vein including SVC in 4 and bilateral veins in 9. Extra-anatomical bypass was performed in 4 cases with unresectable tumors because of severe SVC syndrome. Subclavian-femoral vein bypass was performed in one and internal jugular-femoral vein bypass in 3. In anatomical bypass, 7 cases have been alive now though 11 died, and graft patency rate was 82% in the right and 38% in the left. All 4 cases with extraanatomical bypass showed improvement of SVC syndrome, but died one to seven months postoperatively. In conclusions, radical operation with reconstruction of SVC was effective to long-term survival and improvement of SVC syndrome. Extraanatomical bypass improved postoperative quality of life remarkably.

摘要

在过去16年里,我校附属医院对22例患者同时进行了上腔静脉(SVC)重建手术。其中,19例患有前纵隔肿瘤,3例为晚期肺癌。患者中男性13例,女性9例,年龄在16至70岁之间(平均51.4岁)。其中10例患者存在严重的上腔静脉综合征。前纵隔肿瘤包括10例侵袭性胸腺瘤、2例胸腺霍奇金病、2例精原细胞瘤,另有1例胸腺癌、1例胸腺类癌、1例甲状腺癌、1例软骨肉瘤转移瘤和1例卵黄囊瘤。关于SVC重建,18例患者在根治性切除肿瘤的同时进行了解剖旁路手术。重建左无名静脉5例,重建包括SVC的右无名静脉4例,双侧静脉9例。4例因严重上腔静脉综合征而无法切除肿瘤的患者进行了非解剖旁路手术。其中1例进行了锁骨下-股静脉旁路手术,3例进行了颈内静脉-股静脉旁路手术。在解剖旁路手术中,11例患者死亡,7例存活至今,右侧移植血管通畅率为82%,左侧为38%。所有4例进行非解剖旁路手术的患者上腔静脉综合征均有改善,但术后1至7个月死亡。总之,SVC重建根治性手术对长期生存和改善上腔静脉综合征有效。非解剖旁路手术显著改善了术后生活质量。

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