Marcellin-Little D J, DeYoung D J, Thrall D E, Merrill C L
Department of Companion Animal and Special Species Medicine, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA.
Vet Surg. 1999 Jan-Feb;28(1):54-60. doi: 10.1053/jvet.1999.0054.
To report the occurrence of medullary bone infarction in both femoral canals after bilateral total hip arthroplasty (THA) and the subsequent unilateral development of an osteosarcoma at the site of bone infarction.
Clinical report.
An 8-month-old neutered male Samoyed dog.
Serial physical and radiographic examinations performed at 1, 2, 3, and 5 years after THA. Bone biopsy specimens of the right distal femoral metaphysis were taken 5 years after THA, and a complete necropsy was performed at the time of euthanasia.
Bilateral medullary bone infarction was visible in the femoral canals 1 year after THA and remained visible on subsequent evaluations. An osteosarcoma developed in the right distal femoral metaphysis at the site of infarction, 5 years after THA, and was found to have metastasized widely throughout the body.
Bone infarction may occur in the femoral canal after canine THA.
Bone infarction may be a predisposing factor for the development of osteosarcoma in the femora of dogs with THAs.
报告双侧全髋关节置换术（THA）后双侧股骨髓内骨梗死的发生情况，以及随后在骨梗死部位单侧发生骨肉瘤的情况。
临床报告。
一只8个月大已绝育的雄性萨摩耶犬。
在THA术后1年、2年、3年和5年进行系列体格检查和影像学检查。THA术后5年取右股骨远端干骺端骨活检标本，并在安乐死时进行完整的尸检。
THA术后1年在股骨髓腔内可见双侧髓内骨梗死，在随后的评估中仍可见。THA术后5年，在梗死部位的右股骨远端干骺端发生骨肉瘤，并发现已广泛转移至全身。
犬THA术后股骨髓腔内可能发生骨梗死。
骨梗死可能是接受THA的犬股骨发生骨肉瘤的一个易感因素。
