Puddu P, Ferranti G, Frezzolini A, Colonna L, Cianchini G
Department of Immunodermatology, Istituto Dermopatico dell'Immacolata IRCCS, Rome, Italy.
J Am Acad Dermatol. 1999 Feb;40(2 Pt 2):298-9. doi: 10.1016/s0190-9622(99)70469-x.
We describe the clinical and laboratory findings of a young man with mycosis fungoides. The disease was associated, since the early stages, with autoimmune purpura. Interferon alfa (IFN-alpha) administration improved this patient's condition, both the purpuric eruption and patchy cutaneous lesions, thus suggesting T-cell abnormalities may be responsible for the development of the disease.
我们描述了一名蕈样肉芽肿青年男性的临床和实验室检查结果。自疾病早期起,该病就与自身免疫性紫癜相关。给予α干扰素(IFN-α)改善了该患者的病情,包括紫癜性皮疹和斑片状皮肤损害,因此提示T细胞异常可能是该病发生的原因。