一只雄性Crj:CD(SD)IGS大鼠的自发性松果体瘤。

Spontaneous pinealoma in a male Crj:CD (SD) IGS rat.

作者信息

Furukawa S, Kobayashi K, Usuda K, Tamura T, Miyamoto Y, Hayashi K, Ikeyama S, Goryo M, Okada K

机构信息

Shiraoka Research Station of Biological Science, Nissan Chemical Industries, Ltd., Saitama, Japan.

出版信息

J Vet Med Sci. 1999 Jan;61(1):41-4. doi: 10.1292/jvms.61.41.

DOI:10.1292/jvms.61.41

PMID:10027162

Abstract

A pinealoma (benign) was found in a 61-week-old male Crj:CD (SD) IGS rat. The neoplasm was located between the cerebral hemispheres and the cerebellum. Histologically, the tumor cells consisted of two cell types: large, pale-staining cells and small dark-staining cells. A fibrovascular stroma divided the tumor cells into incomplete lobules or nest structures. Relatively numerous mitoses were noted in the tumor cells. Ultrastructurally, the tumor cells contained dense-cored vesicles, approximately 120 nm in diameter.

摘要

在一只61周龄的雄性Crj:CD(SD)IGS大鼠中发现了一个松果体瘤（良性）。肿瘤位于大脑半球和小脑之间。组织学上，肿瘤细胞由两种细胞类型组成：大的、淡染细胞和小的深染细胞。纤维血管间质将肿瘤细胞分成不完全的小叶或巢状结构。在肿瘤细胞中观察到相对较多的有丝分裂。超微结构上，肿瘤细胞含有直径约120nm的致密核心小泡。