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解读肺功能数据:印度北部成年人中用臂展替代身高的影响

Interpreting spirometric data: impact of substitution of arm span for standing height in adults from North India.

作者信息

Aggarwal A N, Gupta D, Jindal S K

机构信息

Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Chest. 1999 Feb;115(2):557-62. doi: 10.1378/chest.115.2.557.

Abstract

STUDY OBJECTIVE

To evaluate if direct substitution of arm span for height during interpretation of spirometry data leads to any significant statistical or clinical differences in Indian adults, and to compare this method with the use of height estimated indirectly from arm span.

DESIGN

Cross-sectional.

SETTING

Respiratory laboratory of a tertiary referral hospital in North India.

PARTICIPANTS

Two hundred twenty-eight subjects referred for spirometry.

MEASUREMENTS AND RESULTS

Standing height and arm span were measured for all subjects. Spirometry measurements included FVC, FEV1, FEV1/FVC, peak expiratory flow, and maximal midexpiratory flow. Predicted values for each parameter were calculated separately for height, arm span, and height estimated from fixed height:arm span ratio. Results were classified into normal, obstructive, and restrictive defects for each height, arm span, and estimated height measurement, and any abnormality was categorized as mild, moderate, or severe. Arm span exceeded height in 182 (79.82%) subjects. Thirty-seven (16.2%) and 32 (14.0%) results were classified or categorized incorrectly when arm span and estimated height were substituted respectively, for actual height, with a kappa estimate of agreement 0.779 and 0.808, respectively; 17.4% and 11.0% normal results were classified, respectively, as restrictive defects using arm span and estimated height. Limits of agreement, which were almost equally wide for both sets of data, were more than the permissible intraindividual variability for FVC and FEV1.

CONCLUSIONS

The substitution of arm span for height introduces statistically significant changes in spirometry results. Use of height estimated from arm span using fixed ratio also leads to misclassification of data, though less than that caused by use of arm span alone. Height estimated from arm span can be substituted for actual height in patients in whom height cannot be measured reliably. Where racial/ethnic norms for height and arm span correlation are not available, arm span is a reasonable surrogate for standing height.

摘要

研究目的

评估在解读肺功能数据时直接用臂展替代身高是否会在印度成年人中导致任何显著的统计学或临床差异,并将该方法与根据臂展间接估算身高的方法进行比较。

设计

横断面研究。

地点

印度北部一家三级转诊医院的呼吸实验室。

参与者

228名接受肺功能检查的受试者。

测量与结果

测量了所有受试者的站立身高和臂展。肺功能测量指标包括用力肺活量(FVC)、第1秒用力呼气容积(FEV1)、FEV1/FVC、呼气峰值流速和最大呼气中期流速。分别根据身高、臂展以及根据固定的身高:臂展比例估算的身高计算每个参数的预测值。将每个身高、臂展和估算身高测量结果分为正常、阻塞性和限制性缺陷,任何异常分为轻度、中度或重度。182名(79.82%)受试者的臂展超过身高。当分别用臂展和估算身高替代实际身高时,分别有37例(16.2%)和32例(14.0%)结果分类或分级错误,一致性kappa估计值分别为0.779和0.808;分别有17.4%和11.0%的正常结果使用臂展和估算身高时被分类为限制性缺陷。两组数据的一致性界限几乎一样宽,超过了FVC和FEV1允许的个体内变异性。

结论

用臂展替代身高会使肺功能检查结果产生统计学上的显著变化。使用固定比例从臂展估算身高也会导致数据分类错误,尽管比单独使用臂展导致的错误少。在无法可靠测量身高的患者中,可使用从臂展估算的身高替代实际身高。在没有身高与臂展相关性的种族/民族规范时,臂展是站立身高的合理替代指标。

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