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香港的不动杆菌血症:前瞻性研究与综述

Acinetobacter bacteremia in Hong Kong: prospective study and review.

作者信息

Siau H, Yuen K Y, Ho P L, Wong S S, Woo P C

机构信息

Department of Microbiology, University of Hong Kong, Hong Kong.

出版信息

Clin Infect Dis. 1999 Jan;28(1):26-30. doi: 10.1086/515068.

Abstract

The epidemiological characteristics of 18 patients with acinetobacter bacteremia were analyzed. Patients (mean age, 55.5 years) developed bacteremia after an average of 14.1 days of hospitalization. Fifteen of 16 patients survived bacteremia caused by Acinetobacter baumannii. Cultures of blood from the remaining two patients yielded Acinetobacter lwoffii. Most patients (78%) resided in the general ward, while four patients (22%) were under intensive care. Genotyping by arbitrarily primed polymerase chain reaction analysis and the temporal sequence of isolation were more useful than phenotyping by antimicrobial susceptibility in the determination of the source of bacteremia, and the intravascular catheter was the leading infection source (39% of cases). The possibility of an association of glucose with the pathogenesis of acinetobacter infection was raised.

摘要

对18例不动杆菌血症患者的流行病学特征进行了分析。患者(平均年龄55.5岁)在平均住院14.1天后发生菌血症。16例鲍曼不动杆菌引起菌血症的患者中有15例存活。其余2例患者的血培养分离出鲁氏不动杆菌。大多数患者(78%)住在普通病房,4例患者(22%)在重症监护室。在确定菌血症来源方面,任意引物聚合酶链反应分析的基因分型和分离的时间顺序比抗菌药物敏感性表型分析更有用,血管内导管是主要感染源(39%的病例)。提出了葡萄糖与不动杆菌感染发病机制相关的可能性。

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