人类青春期：青春期女孩的24小时雌二醇水平。
Human puberty: 24-hour estradiol in pubertal girls.
作者信息
Boyar R M, Wu R H, Roffwarg H, Kapen S, Weitzman E D, Hellman L, Finkelstein J W
出版信息
J Clin Endocrinol Metab. 1976 Dec;43(6):1418-21. doi: 10.1210/jcem-43-6-1418.
PMID:1002825
Abstract
Plasma luteinizing hormone, follicle-stimulating hormone, and estradiol were measured at 20-minute intervals for 24-hours in seven pubertal premenarchal girls whose sleep was monitored polygraphically. A circadian variation in plasma estradiol was demonstrated with the highest values occurring during the day (1400-1600 hours) and lowest values during sleep, a time when gonadotropin secretion was augmented.
摘要
对7名青春期初潮前女孩进行了24小时的监测，每隔20分钟测量一次血浆促黄体生成素、促卵泡激素和雌二醇，同时用多导睡眠图监测她们的睡眠情况。结果显示，血浆雌二醇存在昼夜变化，白天（14:00 - 16:00）水平最高，睡眠期间最低，而睡眠期间促性腺激素分泌增加。
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