Kubo M, Taguchi K, Fujisue H, Ihara H, Ikoma F
Department of Urology, Kawanishi City Hospital.
Hinyokika Kiyo. 1998 Dec;44(12):883-6.
An 82-year-old man presented with a huge hypogastric tumor. A pelvic computed tomographic scan and magnetic resonance imaging revealed a multiple cystic mass 14 x 10 x 15 cm in diameter. The prostate specific antigen (PSA) value was elevated to 903 ng/ml. Histological examination of the needle biopsy specimens of the prostate revealed moderately differentiated adenocarcinoma. Bone scintigraphy showed a hot area in part of the costa. No other abnormalities were found. The tumor origin was suspected to be the prostate, but the possibility that it was another organ could not be denied completely since the tumor was located in the anterior portion above the bladder. Treatment with luteinizing hormone-releasing hormone agonist and diethylstilbestrol was initiated considering the patient's age. The PSA value returned to normal and the tumor size was reduced markedly after 28 weeks of therapy. Thirty-seven case of prostatic cancer with cystic formation in the Japanese literature are reviewed.
一名82岁男性因巨大的下腹部肿瘤前来就诊。盆腔计算机断层扫描和磁共振成像显示一个直径为14×10×15厘米的多囊性肿块。前列腺特异性抗原(PSA)值升高至903纳克/毫升。前列腺穿刺活检标本的组织学检查显示为中度分化腺癌。骨闪烁显像显示部分肋骨有热点区域。未发现其他异常。肿瘤起源怀疑为前列腺,但由于肿瘤位于膀胱上方的前部,也不能完全排除来自其他器官的可能性。考虑到患者年龄,开始使用促黄体生成素释放激素激动剂和己烯雌酚进行治疗。治疗28周后,PSA值恢复正常,肿瘤大小明显缩小。本文回顾了日本文献中37例伴有囊性形成的前列腺癌病例。