Yamamoto Y, Kondo A, Atoji Y, Tsubone H, Suzuki Y
Laboratory of Veterinary Anatomy, Faculty of Agriculture, Gifu University, Japan.
J Anat. 1998 Nov;193 ( Pt 4)(Pt 4):581-6. doi: 10.1046/j.1469-7580.1998.19340581.x.
Corpuscular nerve endings in the nasal respiratory mucosa of the dog were investigated by immunohistochemical staining specific for protein gene product 9.5 by light and electron microscopy. In the nasal respiratory mucosa, complex corpuscular endings, which displayed bulbous, laminar and varicose expansions, were distributed on the dorsal elevated part of the nasal septum and on the dorsal nasal concha. The endings were 300-500 microm long and 100-250 microm wide. Some axons gave rise to a single ending while others branched into 2 endings. Cryostat sections revealed that the corpuscular endings were located within the nasal respiratory epithelium. On electron microscopy, immunoreactive nerve terminals that contained organelles, including mitochondria and neurofilaments, were observed within the epithelial layer near the lumen of the nasal cavity. Some terminals contacted the goblet cell. Such terminal regions were covered by the cytoplasmic process of ciliated cells and were never exposed to the lumen of the nasal cavity. These nerve endings are probably activated by pressure changes.
通过蛋白质基因产物9.5特异性免疫组织化学染色，利用光学显微镜和电子显微镜对犬鼻呼吸黏膜中的小体神经末梢进行了研究。在鼻呼吸黏膜中，呈现球状、层状和曲张状膨大的复杂小体末梢分布于鼻中隔的背侧隆起部和鼻背甲。这些末梢长300 - 500微米，宽100 - 250微米。一些轴突产生单个末梢，而另一些则分支形成2个末梢。冰冻切片显示小体末梢位于鼻呼吸上皮内。在电子显微镜下，在鼻腔腔面附近的上皮层内观察到含有线粒体和神经丝等细胞器的免疫反应性神经末梢。一些末梢与杯状细胞接触。此类末梢区域被纤毛细胞的胞质突起覆盖，从不暴露于鼻腔腔面。这些神经末梢可能由压力变化激活。
