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[帕金森病患者立体定向丘脑切开术和苍白球切开术的计算机辅助规划:50例患者运动功能的短期评估]

[Stereotaxic thalamotomy and pallidotomy with computerized planning in Parkinson's disease: short-term evaluation of motor function in 50 patients].

作者信息

Ferraz F P, Aguiar P M, Ferraz H B, Bidó J O, Bouza A A, De Andrade L A

机构信息

Universidade Federal de São Paulo (UNIFESP)-Escola Paulista de Medicina (EPM), Brasil.

出版信息

Arq Neuropsiquiatr. 1998 Dec;56(4):789-97. doi: 10.1590/s0004-282x1998000500014.

Abstract

We evaluated the motor function of 50 patients with Parkinson's disease, who underwent stereotaxic surgery with computerized planning, without ventriculography (ventrolateral thalamotomy- VLT- and/or posteroventral pallidotomy- PVP) before and one month after surgery. 27 unilateral TVL, 10 unilateral PVP, 6 bilateral PVP, and 7 TVL with PVP were performed. The motor evaluation was performed with the Unified Parkinson's Disease Rating Scale, motor score, during on and off periods. We observed a global motor improvement in all groups. The improvement of dyskinesias was obtained in the contralateral side of the body, in the PVP groups. From the 50 patients, 16 (32%) presented post-operative complications, 9 of these (56.25%) improved completely, 6 (37.25%) improved partially, and 1 (6.25%) did not improve during the first month. These results were considered satisfactory, and a long term analysis will show whether these benefits are long lasting or not.

摘要

我们评估了50例帕金森病患者的运动功能,这些患者接受了计算机辅助立体定向手术,术前及术后1个月均未行脑室造影(腹外侧丘脑切开术-VLT-和/或腹后苍白球切开术-PVP)。共进行了27例单侧VLT、10例单侧PVP、6例双侧PVP以及7例VLT联合PVP手术。采用统一帕金森病评定量表的运动评分在“开”期和“关”期进行运动评估。我们观察到所有组的整体运动功能均有改善。在PVP组中,身体对侧的异动症得到改善。50例患者中,16例(32%)出现术后并发症,其中9例(56.25%)完全改善,6例(37.25%)部分改善,1例(6.25%)在第一个月未改善。这些结果被认为是令人满意的,长期分析将表明这些益处是否持久。

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