Ferraz F P, Aguiar P M, Ferraz H B, Bidó J O, Bouza A A, De Andrade L A
Universidade Federal de São Paulo (UNIFESP)-Escola Paulista de Medicina (EPM), Brasil.
Arq Neuropsiquiatr. 1998 Dec;56(4):789-97. doi: 10.1590/s0004-282x1998000500014.
We evaluated the motor function of 50 patients with Parkinson's disease, who underwent stereotaxic surgery with computerized planning, without ventriculography (ventrolateral thalamotomy- VLT- and/or posteroventral pallidotomy- PVP) before and one month after surgery. 27 unilateral TVL, 10 unilateral PVP, 6 bilateral PVP, and 7 TVL with PVP were performed. The motor evaluation was performed with the Unified Parkinson's Disease Rating Scale, motor score, during on and off periods. We observed a global motor improvement in all groups. The improvement of dyskinesias was obtained in the contralateral side of the body, in the PVP groups. From the 50 patients, 16 (32%) presented post-operative complications, 9 of these (56.25%) improved completely, 6 (37.25%) improved partially, and 1 (6.25%) did not improve during the first month. These results were considered satisfactory, and a long term analysis will show whether these benefits are long lasting or not.
我们评估了50例帕金森病患者的运动功能,这些患者接受了计算机辅助立体定向手术,术前及术后1个月均未行脑室造影(腹外侧丘脑切开术-VLT-和/或腹后苍白球切开术-PVP)。共进行了27例单侧VLT、10例单侧PVP、6例双侧PVP以及7例VLT联合PVP手术。采用统一帕金森病评定量表的运动评分在“开”期和“关”期进行运动评估。我们观察到所有组的整体运动功能均有改善。在PVP组中,身体对侧的异动症得到改善。50例患者中,16例(32%)出现术后并发症,其中9例(56.25%)完全改善,6例(37.25%)部分改善,1例(6.25%)在第一个月未改善。这些结果被认为是令人满意的,长期分析将表明这些益处是否持久。