Udaka T, Suzuki Y, Kimura H, Miyashita K, Suwaki T, Yoshino T
Department of Surgery, Mitoyo General Hospital, Kagawa, Japan.
Surg Today. 1999;29(2):160-4. doi: 10.1007/BF02482242.
We report herein an unusual case of primary malignant fibrous histiocytoma (MFH) of the ascending colon. A 47-year-old man was admitted to our hospital for further investigations following the discovery of a mass in the right lower quadrant of the abdomen during a medical checkup. Abdominal ultrasonography (US) and computed tomography (CT) demonstrated a mass extending to the right lateral side from the ascending colon. At laparotomy, a tumor was found originating in the ascending colon and infiltrating the right lateral peritoneum. A right hemicolectomy and partial peritoneal dissection were performed followed by an ileotransverse colostomy reconstruction. The resected specimen contained a tumor measuring 7 x 5 x 4 cm, the cut surface of which was yellowish white, and the mucosa of the colon was intact. Based on histological and immunohistochemical inspection, the tumor was diagnosed as MFH of the ascending colon. We reviewed the total 18 known cases of colorectal MFH documented in the literature including our case. After surgery, 4 of 17 patients died of local recurrence, all within 42 months, indicating that early and complete excision of tumor is essential to achieve cure.
我们在此报告一例升结肠原发性恶性纤维组织细胞瘤（MFH）的罕见病例。一名47岁男性在体检时发现右下腹部有肿块，随后入院接受进一步检查。腹部超声（US）和计算机断层扫描（CT）显示一个肿块从升结肠延伸至右侧。剖腹手术时，发现一个起源于升结肠并浸润右侧腹膜的肿瘤。进行了右半结肠切除术和部分腹膜剥离术，随后进行了回肠横结肠造口重建术。切除的标本包含一个大小为7×5×4 cm的肿瘤，其切面为黄白色，结肠黏膜完整。根据组织学和免疫组化检查，该肿瘤被诊断为升结肠MFH。我们回顾了文献中记录的包括我们病例在内的总共18例已知的结直肠MFH病例。手术后，17例患者中有4例死于局部复发，均在42个月内，这表明早期完全切除肿瘤对于实现治愈至关重要。
