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嵌合小鼠色素上皮和视觉细胞层中细胞分布的比较分析。

Comparative analysis of cell distribution in the pigment epithelium and the visual cell layer of chimaeric mice.

作者信息

Sanyal S, Zeilmaker G H

出版信息

J Embryol Exp Morphol. 1976 Oct;36(2):425-30.

PMID:1003080
Abstract

In chimaeras of both rdrdCC in equilibrium ++ cc and rdrdcc in equilibrium ++CC combinations two types of distribution were observed. In a majority of the chimaeras both retinal layers were chimaeric; whereas in a few cases the pigment epithelium was chimaeric but the visual cell layer was made of ++ cells only. No spatial relation was observed in the distribution of the cells in the two layers. The two eyes of the individuals were nearly always identical with regard to occurrence of chimaerism in the two layers. The findings are discussed in the light of the possible site and mode of expression of the rd gene.

摘要

在处于平衡状态的rdrdCC与++cc以及处于平衡状态的rdrdcc与++CC组合的嵌合体中,观察到两种分布类型。在大多数嵌合体中,视网膜的两层均为嵌合的;而在少数情况下,色素上皮是嵌合的,但视觉细胞层仅由++细胞构成。两层中细胞的分布未观察到空间关系。个体的双眼在两层中嵌合现象的发生方面几乎总是相同的。根据rd基因可能的表达位点和方式对这些发现进行了讨论。

相似文献

1
Comparative analysis of cell distribution in the pigment epithelium and the visual cell layer of chimaeric mice.嵌合小鼠色素上皮和视觉细胞层中细胞分布的比较分析。
J Embryol Exp Morphol. 1976 Oct;36(2):425-30.
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On the incidence of unilateral and bilateral colour blindness in heterozygous females.关于杂合子女性中单侧和双侧色盲的发病率
Hum Genet. 1978 Apr 24;41(3):313-23. doi: 10.1007/BF00284765.