Shtark M B, Stratievsky V I, Ratushnjak A S, Voskresenskaja L V, Karasev N P
J Neurobiol. 1976 Nov;7(6):551-66. doi: 10.1002/neu.480070608.
The statistical characteristics of the spontaneous spike activity of rat hippocampal neurons in fields CA1-2 were compared in situ and in tissue culture. Statistical analyses have shown strong similarities in estimators of basic numerical characteristics of interspike interval (SIS) distributions. These similarities may serve as evidence of maintenance of normal functional properties and an "organotypic arrangement" of neurons in tissue culture, and they are also indicative of an intrahippocampal origin of the spontaneous impulse activity in the hippocampus. On the other hand, some differences are noted in the tests of firing patterns. Interpretation of these results leads to some assumptions about mechanisms of the phenomenon under study.
对大鼠海马CA1-2区神经元自发放电活动的统计特征进行了原位和组织培养条件下的比较。统计分析表明，峰间间隔（SIS）分布的基本数值特征估计值具有很强的相似性。这些相似性可能是组织培养中神经元正常功能特性维持和“器官样排列”的证据，也表明海马中自发放电活动起源于海马内部。另一方面，在放电模式测试中发现了一些差异。对这些结果的解释引发了关于所研究现象机制的一些假设。
