Hautmann R, Lutzeyer W
J Urol. 1976 Dec;116(6):687-9. doi: 10.1016/s0022-5347(17)58971-5.
Kidney tissue enzyme patterns from patients with calcium oxalate stone disease were compared to enzyme patterns from healthy and inflamed human kidneys. In the case of oxalate stone disease there was a significantly decreased activity of the glycolytic enzyme aldolase, resulting in a cumulation of oxaloacetate and of oxalic acid. This decrease of the aldolase activity does not completely reveal the cause of calcium oxalate stones but provides a new aspect to the disease.
将草酸钙结石病患者的肾组织酶谱与健康人和发炎的人肾脏的酶谱进行了比较。在草酸结石病的情况下，糖酵解酶醛缩酶的活性显著降低，导致草酰乙酸和草酸的积累。醛缩酶活性的这种降低并未完全揭示草酸钙结石的病因，但为该疾病提供了一个新的视角。
