Takahashi Y, Murai C, Ishii T, Sugamura K, Sasaki T
Department of Clinical, Tohoku University School of Medicine, Sendai, Japan.
Int Rev Immunol. 1998;17(5-6):309-21. doi: 10.3109/08830189809054408.
Viral arthritis occurs transiently in most cases, because the infection is self limiting. The arthropathy associated with human parvovirus B19, however, often lasts for more than 2 years and their clinical symptoms may resemble with those of rheumatoid arthritis. Data have been accumulating for the link of B19 infection with chronic polyarthropathy or rheumatoid arthritis (RA), and we discuss the possible mechanism for the role of B19 in the etiopathology of RA.
在大多数情况下，病毒性关节炎是短暂性的，因为感染是自限性的。然而，与人类细小病毒B19相关的关节病通常会持续两年以上，其临床症状可能与类风湿性关节炎相似。关于B19感染与慢性多关节病或类风湿性关节炎（RA）之间联系的数据不断积累，我们讨论了B19在RA发病机制中可能发挥作用的机制。
