Merle-Vincent F, Chevrel G, Lombard-Bohas C, Felmann C, Meunier P J
Rheumatology and Bone Diseases Unit, Edouard Herriot Teaching Hospital, Lyon, France.
Rev Rhum Engl Ed. 1999 Jan;66(1):46-8.
Two case-reports of metastatic bone disease in patients with bronchial carcinoid tumors illustrate the diagnostic challenges raised by these slowly-growing malignancies of which the primary frequently escapes early identification. The first patient had the typical picture of a primary with a single bone metastasis. Unusual features in the second patient were the large number of bone metastases, involvement of distal skeletal sites, and elevation of serotonin and 5-hydroxyindoleacetic acid levels.