用于皮肤病的中药乳膏分析。
Analysis of Chinese herbal creams prescribed for dermatological conditions.
作者信息
Keane F M, Munn S E, du Vivier A W, Taylor N F, Higgins E M
机构信息
Departments of Dermatology and Clinical Biochemistry, King's College Hospital, London SE5 9RS.
出版信息
BMJ. 1999 Feb 27;318(7183):563-4. doi: 10.1136/bmj.318.7183.563.
Abstract
OBJECTIVE
To determine whether Chinese herbal creams used for the treatment of dermatological conditions contain steroids.
DESIGN
11 herbal creams obtained from patients attending general and paediatric dermatology outpatient clinics were analysed with high resolution gas chromatography and mass spectrometry.
SETTING
Departments of dermatology and clinical biochemistry.
MAIN OUTCOME MEASURE
Presence of steroid.
RESULTS
Eight creams contained dexamethasone at a mean concentration of 456 micrograms/g (range 64 to 1500 micrograms/g). All were applied to areas of sensitive skin such as face and flexures.
CONCLUSION
Greater regulation needs to be imposed on Chinese herbalists to prevent illegal and inappropriate prescribing of potent steroids.
摘要
目的
确定用于治疗皮肤病的中药乳膏是否含有类固醇。
设计
对从普通皮肤科和儿科皮肤科门诊患者处获得的11种中药乳膏进行高分辨率气相色谱和质谱分析。
地点
皮肤科和临床生物化学科。
主要观察指标
类固醇的存在情况。
结果
8种乳膏含有地塞米松，平均浓度为456微克/克（范围为64至1500微克/克）。所有这些乳膏都用于面部和褶皱等敏感皮肤部位。
结论
需要对中医师加强监管，以防止强效类固醇的非法和不当处方。
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