Petzoldt R, Hartwich G, Demmler K
Med Klin. 1976 Nov 26;71(48):2123-6.
Chronic lymphocytic leukemia was diagnosed in three siblings. Familiar occurrence speaks in favor of a predisposition in this disorder of unknown etiology. According to the present status of knowledge endogenous - genetically determined - factors combined with exogenous factors (viruses, radiation exposure, toxic substances) participate in the etiopathogenesis of the different forms of leukemia.
三名兄弟姐妹被诊断出患有慢性淋巴细胞白血病。家族性发病表明这种病因不明的疾病存在易感性。根据目前的知识状况，内源性（基因决定的）因素与外源性因素（病毒、辐射暴露、有毒物质）共同参与了不同类型白血病的病因发病机制。
