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慢性淋巴细胞白血病的家族性发病:三例同胞病例报告(作者译)

[Familial occurrence of chronic lymphocytic leukemia: report of three siblings (author's transl)].

作者信息

Petzoldt R, Hartwich G, Demmler K

出版信息

Med Klin. 1976 Nov 26;71(48):2123-6.

PMID:1004361
Abstract

Chronic lymphocytic leukemia was diagnosed in three siblings. Familiar occurrence speaks in favor of a predisposition in this disorder of unknown etiology. According to the present status of knowledge endogenous - genetically determined - factors combined with exogenous factors (viruses, radiation exposure, toxic substances) participate in the etiopathogenesis of the different forms of leukemia.

摘要

三名兄弟姐妹被诊断出患有慢性淋巴细胞白血病。家族性发病表明这种病因不明的疾病存在易感性。根据目前的知识状况,内源性(基因决定的)因素与外源性因素(病毒、辐射暴露、有毒物质)共同参与了不同类型白血病的病因发病机制。

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