300至10000埃分辨率下环状超螺旋DNA的X射线衍射研究。

X-ray diffraction studies of circular superhelical DNA at 300-10,000-A resolution.

作者信息

Brady G W, Fein D B

出版信息

Nature. 1976 Nov 18;264(5583):231-4. doi: 10.1038/264231a0.

Abstract

X-ray diffraction studies on circular superhelical DNA from bacteriophage PM2 at a very low scattering angle show that it is possible to measure the superhelical scattering function of the molecule. The results suggest that in addition to the primary supercoil, a higher order of supercoiling of the DNA is present, an effect which can be interpreted with a simple analogue.

摘要

对来自噬菌体PM2的环状超螺旋DNA在极低散射角下进行的X射线衍射研究表明，可以测量该分子的超螺旋散射函数。结果表明，除了一级超螺旋外，DNA还存在更高阶的超螺旋，这一效应可用一个简单的类似物来解释。