超螺旋的弹性模型。
Elastic model of supercoiling.
作者信息
Benham C J
出版信息
Proc Natl Acad Sci U S A. 1977 Jun;74(6):2397-401. doi: 10.1073/pnas.74.6.2397.
Abstract
An elastic model for the supercoiling of duplex DNA is developed. The simplest assumptions regarding the elastic properties of double-helical DNA (homogeneous, isotropic, of circular cross section, and remaining straight when unstressed) will generate two orders of superhelicity when stressed. Recent experimental results [Brady, G.W., Fein, D.B. & Brumberger, H. (1976) Nature 264, 231-234] suggest that in supercoiled DNA molecules there are regions where two distinct orders of supercoiling arise, as predicted by this model.
摘要
建立了一个用于双链DNA超螺旋的弹性模型。关于双螺旋DNA弹性特性的最简单假设（均匀、各向同性、圆形横截面且无应力时保持直线）在有应力时会产生两个超螺旋级次。最近的实验结果[布雷迪，G.W.，费恩，D.B.和布伦贝格尔，H.（1976年）《自然》264卷，231 - 234页]表明，在超螺旋DNA分子中存在一些区域，正如该模型所预测的那样，会出现两种不同的超螺旋级次。
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Flexibility of native DNA from the sedimentation behavior as a function of molecular weight and temperature.天然DNA的柔韧性与其沉降行为随分子量和温度的变化关系。
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Partial alteration of secondary structure in native superhelical DNA.天然超螺旋DNA二级结构的部分改变。
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The writhing number of a space curve.空间曲线的扭结数
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Variation of the average rotation angle of the DNA helix and the superhelical turns of covalently closed cyclic lambda DNA.共价闭合环状λ噬菌体DNA的DNA螺旋平均旋转角度和超螺旋匝数的变化
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Further analysis of the altered secondary structure of superhelical DNA. Sensitivity to methylmercuric hydroxide a chemical probe for unpaired bases.超螺旋DNA二级结构改变的进一步分析。对氢氧化甲基汞的敏感性——一种针对未配对碱基的化学探针。
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The interaction of closed circular DNA with intercalative dyes. I. The superhelix density of SV40 DNA in the presence and absence of dye.闭环DNA与嵌入染料的相互作用。I. 存在和不存在染料时SV40 DNA的超螺旋密度。
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Organization of DNA in chromatin.染色质中DNA的组织形式。
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Linking numbers and nucleosomes.连接数与核小体
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9
Action of nicking-closing enzyme on supercoiled and nonsupercoiled closed circular DNA: formation of a Boltzmann distribution of topological isomers.切口封闭酶对超螺旋和非超螺旋闭环DNA的作用：拓扑异构体玻尔兹曼分布的形成
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X-ray diffraction studies of circular superhelical DNA at 300-10,000-A resolution.300至10000埃分辨率下环状超螺旋DNA的X射线衍射研究。
Nature. 1976 Nov 18;264(5583):231-4. doi: 10.1038/264231a0.
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