Pawłowski R
Institute of Forensic Medicine, Medical University of Gdañsk, Poland.
Int J Legal Med. 1999;112(2):139-41. doi: 10.1007/s004140050218.
Amplification products of the HUMFIBRA locus were analysed in a population from Northern Poland using capillary electrophoresis. The most frequent alleles were 21, 22 and 20 with a frequencies of 0.201, 0.179 and 0.167 respectively, and five rare variants were observed with frequencies less than 0.015. A homogeneous allele distribution was found between Polish and Dutch populations and significant differences between Poles and Italians. The high discrimination power (0.963), polymorphic information content (0.849) and heterozygosity confirm the usefulness of HUMFIBRA locus for forensic identification purposes. The application of capillary electrophoresis offers the possibility of precise identification of rare variants.
使用毛细管电泳对来自波兰北部人群的HUMFIBRA基因座扩增产物进行了分析。最常见的等位基因是21、22和20，频率分别为0.201、0.179和0.167，观察到5个罕见变异体，频率小于0.015。在波兰人和荷兰人群之间发现了均匀的等位基因分布，而波兰人和意大利人之间存在显著差异。高鉴别力（0.963）、多态信息含量（0.849）和杂合性证实了HUMFIBRA基因座用于法医鉴定目的的实用性。毛细管电泳的应用为精确鉴定罕见变异体提供了可能性。
