Freeze H H
The Burnham Institute, La Jolla, California 92037, USA.
Biochem Biophys Res Commun. 1999 Feb 16;255(2):189-93. doi: 10.1006/bbrc.1998.9945.
Some genetic defects in protein glycosylation can be treated effectively with dietary supplements of monosaccharides. An easy screening test and non-toxic therapy for potentially lethal disorders should encourage physicians to search for more patients with glycosylation disorders. It should also stimulate research on the occurrence and availability of monosaccharides used for glycoconjugate synthesis and for vertebrate models to study their utilization.
蛋白质糖基化中的一些遗传缺陷可以通过补充单糖饮食有效治疗。一种简单的筛查测试和针对潜在致命疾病的无毒疗法，应该促使医生寻找更多患有糖基化疾病的患者。这也应该刺激对用于糖缀合物合成的单糖的存在和可用性以及用于研究其利用的脊椎动物模型的研究。
