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用于甲状腺癌 I131 给药设施的经验性屏蔽设计数据。

Empirical shielding design data for facilities administering I131 for thyroid carcinoma.

作者信息

Groth M J

机构信息

Department of Diagnostic Physics, Royal Brisbane Hospital.

出版信息

Australas Phys Eng Sci Med. 1998 Dec;21(4):170-8.

Abstract

Retrospective review of the records for 434 post thyroidectomy patients receiving I131 therapy for thyroid carcinoma revealed approximately 75% of the patients were discharged within 48 hours and 90% within 72 hours. Criterion for discharge was an external radiation dose below 25 muSv/hr, measured at one metre anterior to the patient's neck. The time-averaged average dose rate one metre anterior to the neck of a typical patient during the isolation period was 72 muSv/hr, with 90% of the patients below 82 muSv/hr. After correcting for the effects of patient size and scatter, the effective design dose rate from a patient in an isolation room treating two or three patients/week is 105 muSv.m2.hr-1, or 75 muSv.m.hr-1 where only one patient is treated each week. Concrete is the most economical shielding material, with 190 mm filled concrete block walls and 150 mm concrete floors as the minimum recommended shielding for a radioiodine therapy suite. Additional shielding will be required if the suite adjoins (including areas immediately above and below) areas with a high occupancy factor.

摘要

对434例因甲状腺癌接受碘-131治疗的甲状腺切除术后患者的记录进行回顾性分析发现,约75%的患者在48小时内出院,90%在72小时内出院。出院标准是在患者颈部前方1米处测得的外照射剂量低于25微希沃特/小时。典型患者在隔离期间颈部前方1米处的时间平均剂量率为72微希沃特/小时,90%的患者低于82微希沃特/小时。校正患者体型和散射的影响后,每周治疗两三名患者的隔离病房中患者的有效设计剂量率为105微希沃特·平方米·小时-1,若每周仅治疗一名患者则为75微希沃特·米·小时-1。混凝土是最经济的屏蔽材料,对于放射性碘治疗套房,建议至少采用190毫米厚的混凝土砌块墙和150毫米厚的混凝土地板作为屏蔽。如果套房毗邻(包括正上方和正下方区域)人员占用率高的区域,则需要额外的屏蔽。

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