骨髓核糖核酸聚合酶。睾酮对核苷酸掺入核RNA的影响。
Bone marrow ribonucleic acid polymerase. Effect of testosterone on nucleotide incorporation into nuclear RNA.
作者信息
Valladares L E, Cañas P E, Minguell J J
出版信息
Nucleic Acids Res. 1976 Nov;3(11):3077-86. doi: 10.1093/nar/3.11.3077.
Abstract
The incorporation of 3H-UTP into RNA by isolated rat bone marrow nuclei is stimulated by testosterone. This effect is hormone and tissue specific. Using alpha-amanitine and different ionic strength conditions it was found that testosterone enhances preferentially RNA polymerase I activity. The sedimentation pattern of RNA isolated from bone marrow nuclei shows that the synthesis of RNA species within the 14-30 S range is mainly stimulated by the hormone.
摘要
睾酮可刺激分离出的大鼠骨髓细胞核将³H-UTP掺入RNA中。这种作用具有激素和组织特异性。使用α-鹅膏蕈碱和不同离子强度条件发现，睾酮优先增强RNA聚合酶I的活性。从骨髓细胞核中分离出的RNA沉降模式表明，激素主要刺激14 - 30 S范围内RNA种类的合成。
相似文献
1
Bone marrow ribonucleic acid polymerase. Effect of testosterone on nucleotide incorporation into nuclear RNA.骨髓核糖核酸聚合酶。睾酮对核苷酸掺入核RNA的影响。
Nucleic Acids Res. 1976 Nov;3(11):3077-86. doi: 10.1093/nar/3.11.3077.
2
Hormonal control of gene expression: differential activation of rat bone marrow RNA polymerases by erythropoietin and testosterone.基因表达的激素调控：促红细胞生成素和睾酮对大鼠骨髓RNA聚合酶的差异激活
Arch Biol Med Exp. 1979 Oct;12(3):309-18.
3
RNA-polymerase activity in isolated nuclei of developing silkworm embryos.发育中家蚕胚胎分离细胞核中的RNA聚合酶活性
Sov J Dev Biol. 1975 Jul;5(4):350-2.
4
Effect of estradiol on rat uterus DNA-dependent RNA polymerases. Studies with whole nuclei.雌二醇对大鼠子宫DNA依赖性RNA聚合酶的作用。全细胞核研究。
J Biol Chem. 1977 Jul 10;252(13):4607-12.
5
6
Hormonal control of RNA polymerases in rat bone marrow nuclei. The action of erythropoietin and testosterone.大鼠骨髓细胞核中RNA聚合酶的激素调控。促红细胞生成素和睾酮的作用。
Arch Biol Med Exp. 1980 Nov;13(2):247-57.
7
Adrenocorticotropic hormone stimulation of adrenal RNA polymerase I and III activities. Nucleotide incorporation into internal positions and 3' chain termini.促肾上腺皮质激素对肾上腺RNA聚合酶I和III活性的刺激作用。核苷酸掺入内部位置和3'链末端。
Biochemistry. 1975 Jul;14(13):2925-33. doi: 10.1021/bi00684a021.
8
Isolation and characterization of DNA-dependent RNA polymerase A, B and C from rat brain nuclei.大鼠脑细胞核中依赖DNA的RNA聚合酶A、B和C的分离与鉴定
J Neurochem. 1978 Aug;31(2):449-56. doi: 10.1111/j.1471-4159.1978.tb02660.x.
9
Alpha-Amanitin-sensitive DNA-dependent RNA polymerase I from cherry salmon (Oncorhynchus masou) liver nuclei.来自樱花鲑（Oncorhynchus masou）肝细胞核的α-鹅膏蕈碱敏感的DNA依赖性RNA聚合酶I
Biochem Biophys Res Commun. 1982 Jun 30;106(4):1463-8. doi: 10.1016/0006-291x(82)91278-5.
10
In vivo effect of androgen and cycloheximide on the RNA synthesis in isolated nuclei of rat ventral prostates.雄激素和环己酰亚胺对大鼠前列腺分离细胞核中RNA合成的体内效应。
J Biochem. 1978 Dec;84(6):1519-28. doi: 10.1093/oxfordjournals.jbchem.a132277.
本文引用的文献
1
Tables for estimating sedimentation through linear concentration gradients of sucrose solution.用于通过蔗糖溶液线性浓度梯度估算沉降的表格。
Anal Biochem. 1967 Jul;20(1):114-49. doi: 10.1016/0003-2697(67)90271-0.
2
Effect of methyltestosterone on the nucleic acid metabolism of rat bone marrow cells.甲基睾酮对大鼠骨髓细胞核酸代谢的影响。
Proc Soc Exp Biol Med. 1971 Nov;138(2):438-40. doi: 10.3181/00379727-138-35914.
3
Role of DNA-dependent RNA polymerase 3 in the transcription of the tRNA and 5S RNA genes.DNA依赖的RNA聚合酶3在tRNA和5S RNA基因转录中的作用。
Proc Natl Acad Sci U S A. 1974 May;71(5):1790-4. doi: 10.1073/pnas.71.5.1790.
4
Androgen "receptor" in rat liver: cytosol "receptor" deficiency in pseudohermaphrodite male rats.大鼠肝脏中的雄激素“受体”：假性雌雄同体雄性大鼠的胞质“受体”缺陷
Nat New Biol. 1973 Apr 25;242(121):248-50. doi: 10.1038/newbio242248a0.
5
Ribonuclease activity in rat bone marrow nuclei.大鼠骨髓细胞核中的核糖核酸酶活性。
Biochem Biophys Res Commun. 1970 Oct 9;41(1):50-6. doi: 10.1016/0006-291x(70)90467-5.
6
Characteristics of erythropoietin-induced RNA from foetal mouse liver erythropoietic cell cultures and the effects of 5-fluorodeoxyuridine.来自胎鼠肝脏红细胞生成细胞培养物的促红细胞生成素诱导RNA的特征及5-氟脱氧尿苷的作用
Biochim Biophys Acta. 1972 Aug 25;277(2):342-53. doi: 10.1016/0005-2787(72)90416-9.
7
DNA-dependent RNA polymerase levels during the response of human peripheral lymphocytes to phytohemagglutinin.
Cell. 1975 Jan;4(1):51-7. doi: 10.1016/0092-8674(75)90133-6.
8
RNA polymerase activity and uterine growth: Differential stimulation by estradiol, estriol, and nafoxidine.RNA聚合酶活性与子宫生长：雌二醇、雌三醇和萘福昔定的差异刺激作用
Biochemistry. 1976 Apr 6;15(7):1370-4. doi: 10.1021/bi00652a003.
9
Molecular mechanism of action of the male sex hormones.雄性激素的分子作用机制。
J Endocrinol. 1975 May;65(2):287-315. doi: 10.1677/joe.0.0650287.
10
Characterization of a nuclear receptor for testosterone in rat bone marrow.大鼠骨髓中睾酮核受体的特性研究
Steroids. 1975 Jan;25(1):13-21. doi: 10.1016/s0039-128x(75)80003-1.
Zotero 插件