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[乙酰纤维素超滤膜对生物活性物质的渗透性]

[Permeability of acetylcellulose ultrafiltration membranes with regard to biologically active substances].

作者信息

Rozhanskaia T I, Margolina N A, Podsukhina G M, Selezneva A A, Dubiaga V P

出版信息

Prikl Biokhim Mikrobiol. 1976 Mar-Apr;12(2):287-90.

PMID:1005367
Abstract

The permeability of standard Soviet ultrafiltration membranes prepared from cellulose acetates was investigated with respect to biologically active substances (hemoglobin, trypsin, ribonuclease, vitamin B12, hydroxytetracycline) and inorganic salt (KH2PO4). The arrest of a substance by a membrane of a certain structure depended primarily on the size of the substance macromolecule in the solution. The filtration rate was related to the membrane type, pressure gradient and composition of the filtered solution. Potential use of the tested membranes is described.

摘要

对由醋酸纤维素制备的标准苏联超滤膜针对生物活性物质(血红蛋白、胰蛋白酶、核糖核酸酶、维生素B12、羟四环素)和无机盐(KH2PO4)的渗透性进行了研究。某种结构的膜对物质的截留主要取决于溶液中物质大分子的大小。过滤速率与膜的类型、压力梯度和过滤溶液的组成有关。描述了所测试膜的潜在用途。

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