Mietus J, Hausdorff J M, Havlin S, Stanley H E, Goldberger A L
Center for Polymer Studies and Department of Physics, Boston University, Massachusetts 02215.
Phys Rev Lett. 1993 Mar 1;70(9):1343-6. doi: 10.1103/PhysRevLett.70.1343.
We find that the successive increments in the cardiac beat-to-beat intervals of healthy subjects display scale-invariant, long-range anticorrelations (up to 10(4) heart beats). Furthermore, we find that the histogram for the heartbeat intervals increments is well described by a Lévy stable distribution. For a group of subjects with severe heart disease, we find that the distribution is unchanged, but the long-range correlations vanish. Therefore, the different scaling behavior in health and disease must relate to the underlying dynamics of the heartbeat.
我们发现，健康受试者心跳逐搏间期的连续增量呈现出尺度不变的长程反相关性（长达10⁴次心跳）。此外，我们发现心跳间期增量的直方图可以很好地用Lévy稳定分布来描述。对于一组患有严重心脏病的受试者，我们发现分布没有变化，但长程相关性消失了。因此，健康和疾病状态下不同的标度行为必定与心跳的潜在动力学有关。
