Berlan M
C R Seances Soc Biol Fil. 1976 Oct;170(3):672-9.
Noradrénaline or isoprenaline (a beta sympathicomimetic drug) infusion in fasting awake dog provoque a rise of plasmatic FFA. This effect is abolished by administration of propranolol (beta blocking agent) but not by phentolamine (alpha blocking agent). Phentolamine potentiate the rise of FFA in response to noradrenaline but not to isoprenaline. This alpha blocking drug supress the fall of FFA induced by phenylephrine a sympathomimetic drug.
在禁食清醒的狗中输注去甲肾上腺素或异丙肾上腺素(一种β拟交感神经药)会导致血浆游离脂肪酸(FFA)升高。给予普萘洛尔(β受体阻滞剂)可消除这种作用,但给予酚妥拉明(α受体阻滞剂)则不能。酚妥拉明可增强去甲肾上腺素引起的FFA升高,但对异丙肾上腺素无此作用。这种α受体阻断药可抑制去氧肾上腺素(一种拟交感神经药)诱导的FFA下降。