[氢化可的松后中性粒细胞升高被视为骨髓储备量。与脾脏大小有关]
[Rise in neutrophils after hydrocortisone seen as bone marrow reserve mass. Dependency on spleen size].
作者信息
Roth P, Deubelbeiss K A, Lindemann B, Schneider M, Vuilleumier A
出版信息
Schweiz Med Wochenschr. 1976 Oct 2;106(40):1382.
PMID:1006263
Abstract
In 25 patients with a wide range of postmitotic marrow neutrophil mass a linear relationship was observed between the number of postmitotic marrow neutrophils and the rise of blood neutrophils after intravenous injection of 3 mg hydrocortisone/kg. Related to marrow neutrophil cellularity, the response curve was significantly higher in 10 splenectomized patients but greatly depressed in 10 patients with splenomegaly.
摘要
在25例有广泛有丝分裂后骨髓中性粒细胞量的患者中，静脉注射3毫克氢化可的松/千克后，观察到有丝分裂后骨髓中性粒细胞数量与血液中性粒细胞升高之间呈线性关系。与骨髓中性粒细胞细胞密度相关，10例脾切除患者的反应曲线明显更高，但10例脾肿大患者的反应曲线则显著降低。
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