Gurll N, DenBesten L
Lab Anim Sci. 1978 Aug;28(4):428-32.
Human cholesterol gallstone disease has been a frequent and serious problem. A number of animal models have been reviewed for comparative study of cholesterol lithogenesis. These models in general have involved (1) decreasing bile salt excretion, (2) increasing dietary cholesterol, or (3) inducing gallbladder infection or stasis.
人类胆固醇胆结石疾病一直是一个常见且严重的问题。为了对胆固醇结石形成进行比较研究,已对多种动物模型进行了综述。这些模型一般涉及:(1) 减少胆汁盐排泄;(2) 增加膳食胆固醇;或(3) 诱发胆囊感染或淤滞。