[滑膜炎、痤疮、脓疱病、骨肥厚、骨髓炎综合征：16例研究]

[The SAPHO syndrome: a study of 16 cases].

作者信息

Olivé A, Pérez-Andrés R, Rivas A, Holgado S, Casado E, Gumá M, Tena X

机构信息

Sección de Reumatología, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona.

出版信息

Med Clin (Barc). 1999 Jan 23;112(2):61-3.

PMID:10065433

Abstract

The SAPHO syndrome is characterized by synovitis, acne, palmo-plantar pustulosis, hyperostosis and osteitis. SAPHO syndrome has been occasionally described in Spain. We present our experience of 16 cases with the SAPHO syndrome diagnosed between 1984-1995. The predominant clinical symptoms were: anterior thoracic pain (14 cases), sacroiliac pain (7 cases) and peripheral arthritis (2 cases). Cutaneous involvement was characterized by palmo-plantar pustulosis (8 cases) acne (3 cases) and psoriasis (2 cases). The histocompatibility antigen B27 was negative in all cases. A computerized tomographic study revealed involvement of sterno-costo-clavicular and manubriosternal joints (14 cases) and sacroiliitis (8 cases).

摘要

SAPHO综合征的特征为滑膜炎、痤疮、掌跖脓疱病、骨质增生和骨炎。西班牙曾偶尔报道过SAPHO综合征。我们介绍1984年至1995年间确诊的16例SAPHO综合征的诊疗经验。主要临床症状为：胸前区疼痛（14例）、骶髂关节疼痛（7例）和外周关节炎（2例）。皮肤受累表现为掌跖脓疱病（8例）、痤疮（3例）和银屑病（2例）。所有病例的组织相容性抗原B27均为阴性。计算机断层扫描显示胸锁关节和胸骨柄关节受累（14例）以及骶髂关节炎（8例）。