嗜热栖热菌基因组：从基因组学到生物学

Sulfolobus genome: from genomics to biology.

作者信息

Charlebois R L, She Q, Sprott D P, Sensen C W, Garrett R A

机构信息

University of Ottawa, Department of Biology, 30 Marie Curie, Ottawa, Ontario, K1N 6N5, Canada.

出版信息

Curr Opin Microbiol. 1998 Oct;1(5):584-8. doi: 10.1016/s1369-5274(98)80093-3.

DOI:10.1016/s1369-5274(98)80093-3

PMID:10066534

Abstract

Major progress in sequencing the genome of Sulfolobus solfataricus has been closely concerted with the characterization and sequencing of many extrachromosomal genetic elements, including viruses, cryptic plasmids and conjugative plasmids, as well as mobile archaeal introns and transposons. The latter have provided a basis for developing the first generation of vectors that are now being used to study the genetics of Sulfolobus and other Archaea.

摘要

嗜热栖热菌（Sulfolobus solfataricus）基因组测序的重大进展与许多染色体外遗传元件的表征和测序密切相关，这些元件包括病毒、隐蔽质粒和接合质粒，以及可移动的古菌内含子和转座子。后者为开发第一代载体提供了基础，这些载体目前正用于研究嗜热栖热菌和其他古菌的遗传学。