Repin Iu M, El'kin A V, Otten T F, Riasnianskaia T B, Trofimov M A
Probl Tuberk. 1998(6):26-9.
The late outcomes of surgical treatment of 124 patients operated on for pulmonary tuberculosis at many sites were analyzed. Surgery was made in the anatomic variant of typical polysegmental resections involving 3 to 7 bronchopulmonary segments in combination with a number of additional elements. The stable cure rates were 77.7, 71.2, and 64.3% at 3-, 5- and 10-year follow-ups, respectively. The maximum relapse rates at 2- and 3-year follow-up were 9.5 and 9.2%, respectively with variations in some subgroups according to the type of resection, the clinical forms of tuberculosis, the bacteriological activity of the process by surgery and the drug resistance of Mycobacteria. The cumulative adjusted survival rates in the same periods were 92.1, 85.1, and 70%, respectively, with the maximum mortality rate (6.8%) at 3-year follow-up, they being ranged under the influence of the above risk factors. No systematic controlled preventive chemotherapy regimens are a cause of relapses and death in the late periods of follow-ups.
分析了124例接受多部位肺结核手术治疗患者的远期疗效。手术采用典型多节段切除的解剖学变异方式,涉及3至7个支气管肺段,并结合一些其他要素。在3年、5年和10年随访时,稳定治愈率分别为77.7%、71.2%和64.3%。在2年和3年随访时,最大复发率分别为9.5%和9.2%,根据切除类型、肺结核临床类型、手术时病情的细菌学活性以及分枝杆菌的耐药性,某些亚组存在差异。同期累积校正生存率分别为92.1%、85.1%和70%,3年随访时最高死亡率为6.8%,这些受上述风险因素影响而有所不同。在随访后期,没有系统性的预防性化疗方案是复发和死亡的原因。