Dickerson R N, Brown R O, Gervasio J G, Hak E B, Hak L J, Williams J E
Department of Clinical Pharmacy, University of Tennessee, Memphis, 38163, USA.
J Am Coll Nutr. 1999 Feb;18(1):61-8. doi: 10.1080/07315724.1999.10718828.
To determine measured resting energy expenditure (REE) of nonambulatory tube-fed patients with severe neurological neurodevelopmental disabilities.
Twenty patients were prospectively studied. Only steady state indirect calorimetry measurements were taken. All measurements were conducted using a canopy system. Nutritional needs were met entirely by enteral feedings via a permanent ostomy.
REE was widely distributed from 16 kcals/kg/day to 39 kcals/kg/day. The mean REE (888+/-176 kcals/day) of the patients was significantly (p<0.01) lower than predicted as estimated by the Harris-Benedict equations (1081+/-155 kcals/day) and World Health Organization equations (1194+/-167 kcals/day). Fat-free mass (FFM) was the best parameter for predicting REE. Two predictive equations were developed that are not significantly biased and more precise (< or =15% error) than conventional predictive formulas.
Conventional formulas for estimating energy expenditure are inaccurate and generally overestimate measured energy expenditure of nonambulatory patients with severe developmental disabilities.
测定非卧床、经鼻饲管进食的重度神经发育障碍患者的静息能量消耗（REE）。
对20例患者进行前瞻性研究。仅采用稳态间接测热法进行测量。所有测量均使用天篷系统。营养需求完全通过永久性造口进行肠内喂养来满足。
REE范围广泛，从16千卡/千克/天至39千卡/千克/天。患者的平均REE（888±176千卡/天）显著低于（p<0.01）哈里斯-本尼迪克特方程（1081±155千卡/天）和世界卫生组织方程（1194±167千卡/天）预测的数值。去脂体重（FFM）是预测REE的最佳参数。开发了两个预测方程，它们无显著偏差，且比传统预测公式更精确（误差≤15%）。
用于估算能量消耗的传统公式不准确，通常会高估非卧床重度发育障碍患者的实测能量消耗。
