Kirk V G, Morielli A, Brouillette R T
Department of Pediatrics, Alberta Children's Hospital, University of Calgary, Canada.
Dev Med Child Neurol. 1999 Jan;41(1):40-3. doi: 10.1017/s0012162299000079.
Moderate to severe sleep-disordered breathing (SDB) was identified in 20% (17 of 83) of children with spina bifida/myelomeningocele (SB/MM) at the Montreal Children's Hospital. The prevalence of SDB in patients with SB/MM elsewhere has not been determined. To establish current practices for identifying SDB in patients with SB/MM, questionnaires were sent to the coordinators of the 212 spina-bifida clinics in Canada and in the United States. Eighty-six (41%) questionnaires were returned, representing data on 13 349 patients. Although 67% of the responding centers reported availability of cardiorespiratory sleep studies, only 996 (7.5%) patients with SB/MM had been tested and only 418 (3.1%) patients had been diagnosed with SDB. Across clinics, the prevalence of SDB was directly related to the frequency of testing. Of 380 deaths over the past 10 years, SDB and sudden unexplained death during sleep were identified as the cause of death in 49 (12.8%) and 34 (8.9%) patients, respectively. Moderate to severe SDB may not have been identified in a significant number of patients with SB/MM because they have not been tested.
在蒙特利尔儿童医院，20%（83例中的17例）患有脊柱裂/脊髓脊膜膨出（SB/MM）的儿童被诊断出患有中度至重度睡眠呼吸障碍（SDB）。其他地方的SB/MM患者中SDB的患病率尚未确定。为了确定当前在SB/MM患者中识别SDB的做法，向加拿大和美国212家脊柱裂诊所的协调员发送了问卷。86份（41%）问卷被退回，代表了13349例患者的数据。尽管67%的回复中心报告有可进行心肺睡眠研究，但只有996例（7.5%）SB/MM患者接受了检测，只有418例（3.1%）患者被诊断为SDB。在各个诊所中，SDB的患病率与检测频率直接相关。在过去10年的380例死亡病例中，SDB和睡眠中不明原因猝死分别被确定为49例（12.8%）和34例（8.9%）患者的死因。相当数量的SB/MM患者可能未被识别出患有中度至重度SDB，因为他们没有接受检测。
