Quinn M J, Martinez-Garcia C, Berrino F
National Cancer Registration Bureau, Office for National Statistics, London, U.K.
Eur J Cancer. 1998 Dec;34(14 Spec No):2204-11. doi: 10.1016/s0959-8049(98)00323-2.
The objective of this study, part of the wider EUROCARE II collaborative project, was to examine variations by age and country in the relative survival of women from breast cancer in Europe, based on data fro 145,000 cases in 1985-1989 and trends based on (245,000) cases for 1978-1989. Data were supplied by 42 cancer registries in 17 countries to a common protocol. Results for some countries where the participating registries covered only small proportions of the total population may not be representative of the whole country. In 1985-1989 there were wide differences among the 17 countries: survival was above the European average in Iceland, Finland, Sweden, Switzerland, France and Italy; around average in Denmark, The Netherlands, Germany and Spain; below average in Scotland, England and Slovenia; and well below average in Slovakia, Poland and Estonia. In France, Spain and Italy, but not in the U.K., there were wide differences in survival among the participating registries. Survival generally declined with age, particularly in the elderly (75 years and over)--this was most marked in Denmark, Scotland and England. Over the period 1978-1989, 1-year survival improved by 2% overall and 5-year survival by 6%. There were improvements in 5-year survival in all countries except Iceland, Germany, Switzerland and Estonia, and in all age groups except the youngest (15-44 years). It is likely that differences in the access to and quality of care in the various countries played a large part in explaining the differences in survival.
本研究是更广泛的EUROCARE II合作项目的一部分，其目的是基于1985 - 1989年145,000例病例的数据以及1978 - 1989年（245,000）例病例的趋势，研究欧洲乳腺癌女性相对生存率的年龄和国家差异。数据由17个国家的42个癌症登记处按照共同方案提供。部分国家参与登记处覆盖的人口仅占总人口的小比例，其结果可能不代表整个国家的情况。1985 - 1989年，17个国家之间存在很大差异：冰岛、芬兰、瑞典、瑞士、法国和意大利的生存率高于欧洲平均水平；丹麦、荷兰、德国和西班牙的生存率接近平均水平；苏格兰、英格兰和斯洛文尼亚的生存率低于平均水平；斯洛伐克、波兰和爱沙尼亚的生存率远低于平均水平。在法国、西班牙和意大利，但英国不存在这种情况，参与登记处之间的生存率存在很大差异。生存率通常随年龄下降，尤其是在老年人（75岁及以上）中——这在丹麦、苏格兰和英格兰最为明显。在1978 - 1989年期间，总体1年生存率提高了2%，5年生存率提高了6%。除冰岛、德国、瑞士和爱沙尼亚外，所有国家的5年生存率均有所提高；除最年轻年龄组（15 - 44岁）外，所有年龄组的5年生存率也都有所提高。各国在获得医疗服务的机会和医疗质量方面的差异很可能在很大程度上解释了生存率的差异。
